Analysis of the serum IgE levels in nonimmunized rats of various strains by a radioimmunoassay.
作者： T. KARLSSON , J. R. ELLERSON , I. DAHLBOM , H. BENNICH
DOI: 10.1111/J.1365-3083.1979.TB02725.X
关键词:
摘要: An assay, the paper radioimmunosorbent test (PRIST) for measurement of total serum IgE in rat, that allows down to a level 0.25 ng/ml, is described. With this assay it has been demonstrated significant differences exist normal levels non-immunized rats. These are strain-dependent, and strains may be classified as low (less than 50 ng/ml), medium (50--300 ng/ml) or high (greater 300 levels. The not sex-dependent. Environmental factors have pronounced influence, optimal housing conditions resulting stable while suboptimal result with great fluctuations. Hybridization experiments suggest multigenic control, having dominating suppressor effect.
sci-hub.se 参考文章(16)
H. Bennich, S. G. O. Johansson, H. von Bahr-Lindström, T. Karlsson, Function and Structure of Immunoglobulin E (IgE) Springer, Boston, MA. pp. 175- 197 ,(1976) , 10.1007/978-1-4613-4304-2_8
Hans Bennich, S. Gunnar O. Johansson, Structure and Function of Human Immunoglobulin E Advances in Immunology. ,vol. 13, pp. 1- 55 ,(1971) , 10.1016/S0065-2776(08)60182-0
Rowe Ds, Radioactive single radial diffusion: a method for increasing the sensitivity of immunochemical quantification of proteins in agar gel. Bulletin of The World Health Organization. ,vol. 40, pp. 613- 616 ,(1969)
Teruko Ishizaka, Joseph F. Urban, Kimishige Ishizaka, IgE formation in the rat following infection with Nippostrongylus brasiliensis: I. Proliferation and differentiation of IgE-bearing cells Cellular Immunology. ,vol. 22, pp. 248- 261 ,(1976) , 10.1016/0008-8749(76)90027-7
Kimishige Ishizaka, Teruko Ishizaka, Hirokazu Okudaira, Hervé Bazin, Ontogeny of IgE-Bearing Lymphocytes in the Rat Journal of Immunology. ,vol. 120, pp. 655- 660 ,(1978)
Herve Bazin, Dennis Carson, Henry Metzger, Simple radio-immunoassay for the measurement of human and rat IgE levels by ammonium sulfate precipitation. Journal of Immunology. ,vol. 115, pp. 561- 563 ,(1975)
Kurt J. Bloch, Dennis Carson, Henry Metzger, Serum IgE levels during the potentiated reagin response to egg albumin in rats infected with Nippostrongylus brasiliensis. Journal of Immunology. ,vol. 114, pp. 521- 523 ,(1975)
JERKER PORATH, ROLF AXÉN, SVERKER ERNBACK, Chemical Coupling of Proteins to Agarose Nature. ,vol. 215, pp. 1491- 1492 ,(1967) , 10.1038/2151491A0
ELLEN JARRETT, HERVÉ BAZIN, Elevation of total serum IgE in rats following helminth parasite infection Nature. ,vol. 251, pp. 613- 614 ,(1974) , 10.1038/251613A0
T. KARLSSON, J. R. ELLERSON, D. M. HAIG, E. E. E. JARRETT, H. BENNICH, A Radioimmunoassay for Evaluation of the IgE and IgG Antibody Responses in the Rat Scandinavian Journal of Immunology. ,vol. 9, pp. 229- 238 ,(1979) , 10.1111/J.1365-3083.1979.TB02726.X