作者: Pradip Tekade , Bhagyashri Tale , Sonal Bajaj
DOI: 10.1134/S0036024419090188
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摘要: Ultrasonic studies of (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanoic acid (NPTLU), 2-(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-oxoethyl)isoindoline-1,3-dione (C‑BI-CL-L), 2-(4-methyl-1-(2-(4-nitrophenyl)-1H-benzo [d]imidazol-1-yl) -1-oxopentan-2-yl)isoindoline-1,3-dione (C-BI-NO2-L), 2-(1-(2-(4-nitrophenyl)-1H-benzo[d]imidazol-1-yl)-1-oxobutan-2-yl)-2,3-dihydroinden-1-one (C-BI-NO2-G), 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(4-oxo-2-phenylquinazolin-3(4H)-yl) acetamide (C-QA-GL), and 1-(2-((4-oxo-2-phenylquinqxolin-3(4H)-yl)carbamoyl)benzoyl)pyrrolidine-2-carboxylic (C-QA-PR) in solution polar non-polar solvent various concentrations at 303–318 K. Density ultrasonic velocity measured with the help these data, different thermo-acoustical parameters viz. adiabatic compressibility, intermolecular free length, acoustic impedance, surface tension, Rao’s constant, molar volume, Wada’s constant calculated using standard formulas. The variation concentration temperature studied graphical representations parameters. Ethyl alcohol DMSO were chosen as solvents, respectively. properties reveals presence specific molecular interactions solute used, which will give information regarding drug transmission absorption.