Subclinical thyroid dysfunction and blood pressure: a community-based study.
作者： John P. Walsh , Alexandra P. Bremner , Max K. Bulsara , Peter O'Leary , Peter J. Leedman
DOI: 10.1111/J.1365-2265.2006.02619.X
关键词:
摘要: Objective Overt hypothyroidism and hyperthyroidism are associated with hypertension, but it is uncertain whether the same true of subclinical hyperthyroidism. Design, subjects measurements Cross-sectional study 2033 participants (aged 17-89 years) in Busselton Thyroid Study who did not have a history thyroid disease. Systolic blood pressure (SBP), diastolic (DBP) prevalence hypertension (defined as SBP >or=140 mmHg, DBP >or=90 mmHg or on treatment for hypertension) dysfunction euthyroid were compared using linear regression models. Subjects treated (N = 299) excluded from analyses included prevalence. Results Mean SBP, differ significantly between 105) 1859), nor they serum TSH concentrations upper reference range (2.0-4.0 mU/l; N 418) those lower (0.4-2.0 1441). The was higher than (prevalence odds ratio 2.8, 95% confidence interval 1.3-6.0 adjusted age, age(2) sex), this based small number 35). Conclusions Subclinical hypertension. observed association requires confirmation larger sample.
sci-hub.se 参考文章(40)
Marcus Dörr, Birger Wolff, Daniel M. Robinson, Ulrich John, Jan Lüdemann, Wieland Meng, Stephan B. Felix, Henry Völzke, The association of thyroid function with cardiac mass and left ventricular hypertrophy. The Journal of Clinical Endocrinology and Metabolism. ,vol. 90, pp. 673- 677 ,(2005) , 10.1210/JC.2004-1554
Sara Danzi, Irwin Klein, Thyroid hormone and blood pressure regulation Current Hypertension Reports. ,vol. 5, pp. 513- 520 ,(2003) , 10.1007/S11906-003-0060-7
Anne R. Cappola, Linda P. Fried, Alice M. Arnold, Mark D. Danese, Lewis H. Kuller, Gregory L. Burke, Russell P. Tracy, Paul W. Ladenson, Thyroid Status, Cardiovascular Risk, and Mortality in Older Adults JAMA. ,vol. 295, pp. 1033- 1041 ,(2006) , 10.1001/JAMA.295.9.1033
J. Faber, L. Petersen, N. Wiinberg, S. Schifter, J. Mehlsen, Hemodynamic Changes After Levothyroxine Treatment in Subclinical Hypothyroidism Thyroid. ,vol. 12, pp. 319- 324 ,(2002) , 10.1089/10507250252949450
Ross Ihaka, Robert Gentleman, R: A Language for Data Analysis and Graphics Journal of Computational and Graphical Statistics. ,vol. 5, pp. 299- 314 ,(1996) , 10.1080/10618600.1996.10474713
Toshiki Nagasaki, Masaaki Inaba, Yasuro Kumeda, Yoshikazu Hiura, Kumi Shirakawa, Shinsuke Yamada, Yasuko Henmi, Eiji Ishimura, Yoshiki Nishizawa, Increased Pulse Wave Velocity in Subclinical Hypothyroidism The Journal of Clinical Endocrinology and Metabolism. ,vol. 91, pp. 154- 158 ,(2006) , 10.1210/JC.2005-1342
W. M. G. TUNBRIDGE, D. C. EVERED, R. HALL, D. APPLETON, M. BREWIS, F. CLARK, J. GRIMLEY EVANS, E. YOUNG, T. BIRD, P. A. SMITH, LIPID PROFILES AND CARDIOVASCULAR DISEASE IN THE WHICKHAM AREA WITH PARTICULAR REFERENCE TO THYROID FAILURE Clinical Endocrinology. ,vol. 7, pp. 495- 508 ,(1977) , 10.1111/J.1365-2265.1977.TB01341.X
R. AREM, R. ROKEY, C. KIEFE, D.A. ESCALANTE, A. RODRIGUEZ, Cardiac systolic and diastolic function at rest and exercise in subclinical hypothyroidism: effect of thyroid hormone therapy. Thyroid. ,vol. 6, pp. 397- 402 ,(1996) , 10.1089/THY.1996.6.397
N. Manji, K. Boelaert, M. C. Sheppard, R. L. Holder, S. C. Gough, J. A. Franklyn, Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects. Clinical Endocrinology. ,vol. 64, pp. 125- 128 ,(2006) , 10.1111/J.1365-2265.2006.02433.X
J.A. Franklyn, P. Maisonneuve, M.C. Sheppard, J. Betteridge, P. Boyle, Mortality after the Treatment of Hyperthyroidism with Radioactive Iodine New England Journal of Medicine. ,vol. 338, pp. 712- 718 ,(1998) , 10.1056/NEJM199803123381103