Myocardial metabolism on off-pump surgery; a randomized study of 50 cases.

作者: Sahlman A. , Ahonen J. , Nemlander A. , Salmenperä M. , Eriksson H.

DOI: 10.1080/14017430310001726

关键词:

摘要: Objective --To study the inflammatory reaction and myocardial metabolism in off-pump on-pump coronary artery bypass patients. Design --Fifty patients were randomized to or operations. Myocardial biopsies taken determine inflammation (glutathione (GSH), superoxide dismutase (SOD) myeloperoxidase (MP)) plasma samples for indicators of oxidative stress (conjugated dienes (s-BDC), products proteins (s-ox-Prot) low-density lipoprotein (LDL)-total peroxyl radical trapping antioxidant potential (s-TRAP)). Results --s-ox-Prot 10 r min was 2.11 - 0.75 vs 2.69 0.60 ( p = 0.014), s-TRAP 5 861 180 969 192 0.032) 857 176 985 166 0.011), GSH 0.55 0.19 0.72 1.16 0.0...

参考文章(26)
Masahiro Takada, Satoru Ikenoya, Teruaki Yuzuriha, Kouichi Katayama, Simultaneous determination of reduced and oxidized ubiquinones. Methods in Enzymology. ,vol. 105, pp. 147- 155 ,(1984) , 10.1016/S0076-6879(84)05020-5
Hannu J. Toivonen, Markku Ahotupa, Free radical reaction products and antioxidant capacity in arterial plasma during coronary artery bypass grafting The Journal of Thoracic and Cardiovascular Surgery. ,vol. 108, pp. 140- 147 ,(1994) , 10.1016/S0022-5223(94)70230-6
E BUFFOLO, J ANDRADE, J BRANCO, L AGUIAR, E RIBEIRO, A JATENE, Myocardial revascularization without extracorporeal circulation. Seven-year experience in 593 cases. European Journal of Cardio-Thoracic Surgery. ,vol. 4, pp. 504- 508 ,(1990) , 10.1016/1010-7940(90)90174-X
Peter Riis Hansen, Role of Neutrophils in Myocardial Ischemia and Reperfusion Circulation. ,vol. 91, pp. 1872- 1885 ,(1995) , 10.1161/01.CIR.91.6.1872
Jarmo K. Laihia, Christer T. Jansén, Markku Ahotupa, Lucigenin and linoleate enhanced chemiluminescent assay for superoxide dismutase activity Free Radical Biology and Medicine. ,vol. 14, pp. 457- 461 ,(1993) , 10.1016/0891-5849(93)90102-Z
N MOAT, D SHORE, T EVANS, Organ dysfunction and cardiopulmonary bypass: the role of complement and complement regulatory proteins European Journal of Cardio-Thoracic Surgery. ,vol. 7, pp. 563- 573 ,(1993) , 10.1016/1010-7940(93)90241-3
Kazuo Suzuki, Hiromi Ota, Sumiko Sasagawa, Tatsuichiro Sakatani, Toshio Fujikura, Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Analytical Biochemistry. ,vol. 132, pp. 345- 352 ,(1983) , 10.1016/0003-2697(83)90019-2
Ryszard Kalawski, Pawel Bugajski, Juliusz Smielecki, Henryk Wysocki, Roman Olszewski, Ranjit More, Desmond J. Sheridan, Tomasz Siminiak, Soluble adhesion molecules in reperfusion during coronary bypass grafting European Journal of Cardio-Thoracic Surgery. ,vol. 14, pp. 290- 295 ,(1998) , 10.1016/S1010-7940(98)00197-3