High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear of children with a history of recurrent acute otitis media.

摘要: Both bacteria and viruses play a role in the development of acute otitis media, however, importance specific is unclear. In this study molecular methods were used to determine presence nucleic acids human rhinoviruses (HRV; types A, B, C), respiratory syncytial (RSV; A B), bocavirus (HBoV), adenovirus, enterovirus, coronaviruses (229E, HKU1, NL63, OC43), influenza (types parainfluenza 1, 2, 3, 4A, 4B), metapneumovirus, polyomaviruses (KI WU) nasopharynx children between 6 36 months age either with (n = 180) or without 66) history recurrent media 238 middle ear effusion samples collected from 143 media. The co-detection these Streptococcus pneumoniae, nontypeable Haemophilus influenzae, Moraxella catarrhalis was analyzed. HRV (58.3% vs. 42.4%), HBoV (52.2% 19.7%), (36.1% 15.2%), (29.4% 9.1%), adenovirus (25.0% 6.1%), RSV (27.8% 9.1%) detected significantly more often compared healthy children. predominant 46% Since frequently both etiological remains uncertain, anti-viral therapies may be beneficial future treatment prevention strategies for