作者: Scott A. Sasse , Richard B. Berry , Tan K. Nguyen , Richard W. Light , C. Kees Mahutte
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摘要: Breath-holding serves as a model for studying gas exchange during clinical situations in which cessation of ventilation occurs. We chose to examine the arterial blood changes that occurred breath-holding, when breath-holding was initiated from functional residual capacity (FRC) while breathing room air. Eight normal subjects who had radial artery catheter placed another study were taught breath-hold on command FRC. FRC determined using respiratory inductance plethysmography. Arterial specimens obtained at 5-s intervals until termination breath-holding. The average time (±SD) 35 (±10 s). PaO 2 , PaCO and pH values plotted against individually fit logistic equations each subject. fell by mean 50 mm Hg first s under these conditions, Pco rose 10.2 0.07 s. rapid decline is greater than previously reported different methods should be considered there an interruption oxygenation are similar those paralyzed apneic patients.