Retinoic acid and interferon combination studies in human cancer

作者: Scott M. Lippman , Bonnie S. Glisson , John J. Kavanagh , Reuben Lotan , Waun Ki Hong

DOI: 10.1016/0959-8049(93)90618-P

关键词:

摘要: Retinoic acid and interferon-alpha have limited single-agent activity in advanced cancer. Cell culture data indicate that combination these agents enhanced (modulating growth differentiation) a number of malignant cell types. Recent clinical work squamous carcinoma reports major with this regimen. This paper reviews the preclinical testing retinoic interferons presents recent integrating radiotherapy locally cervical

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