From tissue to molecular phenotyping: pre-analytical requirements heidelberg experience.
作者： Thomas R. Muley , Philipp A. Schnabel , Hendrik Dienemann , Felix Jf. Herth , Michael Meister
DOI: 10.3978/J.ISSN.2218-6751.2011.12.07
关键词:
摘要: Lung cancer is a leading cause of tumor-related death worldwide through years. Efforts to individualize lung therapy improve prognosis nowadays employ molecular analyses besides routine histopathological examination tissue samples. In general, tissues are provided by bronchoscopy, CT-guided procedures or surgery. The sequence removal, storage, and processing has considerable impact on the success reliability subsequent biological will supposedly also influence therapeutic decisions. There still an ongoing need for updated statements about minimal requirements sampling diagnosis at international level certified/accredited quality control programs procedures. Several these issues may have be adjusted individual local conditions. We present several aspects experiences gained in Thoraxklinik University Hospital Heidelberg (TK-HD) with pre-analytical requirements.
amegroups.com参考文章(44)
Pedro Gonzalez, J. Samuel Zigler, David L. Epstein, Teresa Borrás, Identification and Isolation of Differentially Expressed Genes from Very Small Tissue Samples BioTechniques. ,vol. 26, pp. 884- 892 ,(1999) , 10.2144/99265ST01
Schirmacher P, Koleganova N, Herpel E, Tissue bank of the National Centre for Tumour Disease. An innovative platform for translational tumour Pathologe. pp. 204- ,(2008) , 10.1007/S00292-008-1067-2
Andreas Schroeder, Odilo Mueller, Susanne Stocker, Ruediger Salowsky, Michael Leiber, Marcus Gassmann, Samar Lightfoot, Wolfram Menzel, Martin Granzow, Thomas Ragg, The RIN: an RNA integrity number for assigning integrity values to RNA measurements BMC Molecular Biology. ,vol. 7, pp. 3- 3 ,(2006) , 10.1186/1471-2199-7-3
Ambrogio Fassina, M Corradin, D Zardo, Rocco Cappellesso, F Corbetti, Matteo Fassan, None, Role and accuracy of rapid on-site evaluation of CT-guided fine needle aspiration cytology of lung nodules Cytopathology. ,vol. 22, pp. 306- 312 ,(2011) , 10.1111/J.1365-2303.2010.00802.X
Bernd Lamprecht, Peter Porsch, Christian Pirich, Michael Studnicka, Electromagnetic Navigation Bronchoscopy in Combination with PET-CT and Rapid On-site Cytopathologic Examination for Diagnosis of Peripheral Lung Lesions Lung. ,vol. 187, pp. 55- 59 ,(2009) , 10.1007/S00408-008-9120-8
Neeta Somaiah, George R. Simon, Molecular Targeted Agents and Biologic Therapies for Lung Cancer Journal of Thoracic Oncology. ,vol. 6, pp. S1758- S1785 ,(2011) , 10.1097/01.JTO.0000407557.30793.A6
Esther Herpel, Christoph Röcken, Heike Manke, Peter Schirmacher, Christa Flechtenmacher, Quality management and accreditation of research tissue banks: experience of the National Center for Tumor Diseases (NCT) Heidelberg Virchows Archiv. ,vol. 457, pp. 741- 747 ,(2010) , 10.1007/S00428-010-0998-1
Yun-Chung Cheung, John Wen-Cheng Chang, Jia-Juan Hsieh, Gigin Lin, Ying-Huang Tsai, Adequacy and complications of computed tomography-guided core needle biopsy on non-small cell lung cancers for epidermal growth factor receptor mutations demonstration: 18-gauge or 20-gauge biopsy needle Lung Cancer. ,vol. 67, pp. 166- 169 ,(2010) , 10.1016/J.LUNGCAN.2009.04.007
Roy S. Herbst, Scott M. Lippman, Molecular signatures of lung cancer--toward personalized therapy. The New England Journal of Medicine. ,vol. 356, pp. 76- 78 ,(2007) , 10.1056/NEJME068218
Ping Gu, Yi-Zhuo Zhao, Li-Yan Jiang, Wei Zhang, Yu Xin, Bao-Hui Han, Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: A systematic review and meta-analysis European Journal of Cancer. ,vol. 45, pp. 1389- 1396 ,(2009) , 10.1016/J.EJCA.2008.11.043