Pulse Wave Analysis of the Aortic Pressure Waveform in Severe Left Ventricular Systolic Dysfunction

摘要: Background— The effect of moderate left ventricular systolic dysfunction (LVSD) on ventricular/vascular coupling and the aortic pressure waveform (AoPW) has been well described, but severe LVSD not.Methods Results— We used noninvasive, high-fidelity tonometry radial artery a mathematical transfer function to generate AoPW in 25 treated patients with (mean LV ejection fraction, 24±8.8%; range, 11% 40%; 21 <30%). Pulse wave analysis was characterize compared pulse performed normal subjects matched for age, gender, height, body mass index, heart rate. Measurements obtained using indicated features poor stroke performance also reduced indices arterial stiffness: increased travel time (147±10 ms versus 132±21 ms; P<0.001); decreased duration reflected (134±24 167±26 P<0.001);...