The effect of embryo quality on subsequent pregnancy rates after in vitro fertilization
作者： Mithat Erenus , Christo Zouves , Pathma Rajamahendran , Susanne Leung , Margo Fluker
DOI: 10.1016/S0015-0282(16)54603-2
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摘要: Objective To determine if a simple morphological classification of embryos was predictive subsequent pregnancy. Design Prospective case series. Setting University-based in vitro fertilization (IVF) program. Patients, Participants Consecutive embryo transfer (ET) cycles (n = 206). Interventions Embryos were classified into three grades: (1) equal-size blastomeres with no fragmentation; (2) unequal-size blastomeres; and (3) evidence fragmentation. Main Outcome Measures Embryo quality, age, indication for IVF, stimulation protocol evaluated their effect on pregnancy rates (PR's). Results In which the best transferred grade 3, 2, or 1, clinical PRs per ET 0% (0/11 cycles), 12.8% (6/47 cycles, P 0.0011) patient's age ( 0.0044) only variables that affected PRs. Conclusion The more than two good quality had positive effect, negative after IVF-ET.
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sci-hub.se 参考文章(10)
George A. Hill, Melanie Freeman, Maria Cristina Bastias, B. Jane Rogers, Carl M. Herbert, Kevin G. Osteen, Anne Colston Wentz, The influence of oocyte maturity and embryo quality on pregnancy rate in a program for in vitro fertilization-embryo transfer. Fertility and Sterility. ,vol. 52, pp. 801- 806 ,(1989) , 10.1016/S0015-0282(16)61034-8
Carl Wood, Rex McMaster, George Rennie, Alan Trounson, John Leeton, Factors influencing pregnancy rates following in vitro fertilization and embryo transfer Fertility and Sterility. ,vol. 43, pp. 245- 250 ,(1985) , 10.1016/S0015-0282(16)48380-9
F. Puissant, M. Van Rysselberge, P. Barlow, J. Deweze, F. Leroy, Embryo scoring as a prognostic tool in IVF treatment Human Reproduction. ,vol. 2, pp. 705- 708 ,(1987) , 10.1093/OXFORDJOURNALS.HUMREP.A136618
R. G. Edwards, S. B. Fishel, J. Cohen, C. B. Fehilly, J. M. Purdy, J. M. Slater, P. C. Steptoe, J. M. Webster, Factors influencing the success of in vitro fertilization for alleviating human infertility Journal of Assisted Reproduction and Genetics. ,vol. 1, pp. 3- 23 ,(1984) , 10.1007/BF01129615
LUCINDA L. VEECK, Oocyte assessment and biological performance. Annals of the New York Academy of Sciences. ,vol. 541, pp. 259- 274 ,(1988) , 10.1111/J.1749-6632.1988.TB22263.X
C. Magnusson, T. Hillensjö, L. Hamberger, L. Nilsson, Oxygen consumption by human oocytes and blastocysts grown in vitro. Human Reproduction. ,vol. 1, pp. 183- 184 ,(1986) , 10.1093/OXFORDJOURNALS.HUMREP.A136377
Stephen J. Harris, Michael P. Milligan, Gordon M. Masson, K. John Dennis, Improved separation of motile sperm in asthenospermia and its application to artificial insemination homologous (AIH) Fertility and Sterility. ,vol. 36, pp. 219- 221 ,(1981) , 10.1016/S0015-0282(16)45682-7
Paul Claman, D. Randall Armant, Machelle M. Seibel, Tzong-An Wang, Selwyn P. Oskowitz, Melvin L. Taymor, The impact of embryo quality and quantity on implantation and the establishment of viable pregnancies Journal of Assisted Reproduction and Genetics. ,vol. 4, pp. 218- 222 ,(1987) , 10.1007/BF01533759
R. G. Edwards, Diagnostic methods for human gametes and embryos. Human Reproduction. ,vol. 2, pp. 415- 420 ,(1987) , 10.1093/OXFORDJOURNALS.HUMREP.A136560
H.J. Leese, M.A.K. Hooper, R.G. Edwards, M.J. Ashwood-Smith, Uptake of pyruvate by early human embryos determined by a non-invasive technique Human Reproduction. ,vol. 1, pp. 181- 182 ,(1986) , 10.1093/OXFORDJOURNALS.HUMREP.A136376