Circular RNAs are miRNA sponges and can be used as a new class of biomarker.

作者: Franceli Rodrigues Kulcheski , Ana Paula Christoff , Rogerio Margis , None

DOI: 10.1016/J.JBIOTEC.2016.09.011

关键词:

摘要: … Additionally, this web tool assists in the design of siRNAs directed to circRNA; the 21 nt siRNA targets the junctional sequences of circRNA and can be used in the study of circRNA …

参考文章(105)
Haruhiko Siomi, Mikiko C. Siomi, Posttranscriptional regulation of microRNA biogenesis in animals. Molecular Cell. ,vol. 38, pp. 323- 332 ,(2010) , 10.1016/J.MOLCEL.2010.03.013
Steve Hoffmann, Christian Otto, Gero Doose, Andrea Tanzer, David Langenberger, Sabina Christ, Manfred Kunz, Lesca M Holdt, Daniel Teupser, Jörg Hackermüller, Peter F Stadler, A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection Genome Biology. ,vol. 15, pp. 1- 11 ,(2014) , 10.1186/GB-2014-15-2-R34
Adam Ameur, Anna Wetterbom, Lars Feuk, Ulf Gyllensten, Global and unbiased detection of splice junctions from RNA-seq data Genome Biology. ,vol. 11, pp. 1- 9 ,(2010) , 10.1186/GB-2010-11-3-R34
Reut Ashwal-Fluss, Markus Meyer, Nagarjuna Reddy Pamudurti, Andranik Ivanov, Osnat Bartok, Mor Hanan, Naveh Evantal, Sebastian Memczak, Nikolaus Rajewsky, Sebastian Kadener, circRNA Biogenesis Competes with Pre-mRNA Splicing Molecular Cell. ,vol. 56, pp. 55- 66 ,(2014) , 10.1016/J.MOLCEL.2014.08.019
Yang Zhang, Xiao-Ou Zhang, Tian Chen, Jian-Feng Xiang, Qing-Fei Yin, Yu-Hang Xing, Shanshan Zhu, Li Yang, Ling-Ling Chen, Circular Intronic Long Noncoding RNAs Molecular Cell. ,vol. 51, pp. 792- 806 ,(2013) , 10.1016/J.MOLCEL.2013.08.017
Quentin Vicens, Eric Westhof, Biogenesis of Circular RNAs. Cell. ,vol. 159, pp. 13- 14 ,(2014) , 10.1016/J.CELL.2014.09.005
Sebastian Memczak, Marvin Jens, Antigoni Elefsinioti, Francesca Torti, Janna Krueger, Agnieszka Rybak, Luisa Maier, Sebastian D. Mackowiak, Lea H. Gregersen, Mathias Munschauer, Alexander Loewer, Ulrike Ziebold, Markus Landthaler, Christine Kocks, Ferdinand le Noble, Nikolaus Rajewsky, Circular RNAs are a large class of animal RNAs with regulatory potency Nature. ,vol. 495, pp. 333- 338 ,(2013) , 10.1038/NATURE11928
Jacek Krol, Inga Loedige, Witold Filipowicz, The widespread regulation of microRNA biogenesis, function and decay Nature Reviews Genetics. ,vol. 11, pp. 597- 610 ,(2010) , 10.1038/NRG2843
Thomas B. Hansen, Jørgen Kjems, Christian K. Damgaard, Circular RNA and miR-7 in Cancer Cancer Research. ,vol. 73, pp. 5609- 5612 ,(2013) , 10.1158/0008-5472.CAN-13-1568
Yun-Ju Chen, Pei-Hsuan Chien, Wen-Shu Chen, Yu-Fong Chien, Ya-Ying Hsu, Li-Yun Wang, Jhen-Yu Chen, Chih-Wen Lin, Tzung-Chi Huang, Yung-Luen Yu, Wei-Chien Huang, Hepatitis B Virus-Encoded X Protein Downregulates EGFR Expression via Inducing MicroRNA-7 in Hepatocellular Carcinoma Cells. Evidence-based Complementary and Alternative Medicine. ,vol. 2013, pp. 682380- 682380 ,(2013) , 10.1155/2013/682380