The direction of actin polymerization for vesicle fission suggested from membranes tubulated by the EFC/F-BAR domain protein FBP17

作者: Shiro Suetsugu

DOI: 10.1016/J.FEBSLET.2009.10.019

关键词:

摘要: Actin polymerization mediated by the Arp2/3 complex is essential for membrane tubulation, vesicle formation and fission during clathrin-dependent endocytosis. However, mechanism which polymerizing actin filaments participate in has remained unclear. Our analyses revealed that occurs toward FBP17-induced tubules, are considered to be generated endocytic formation. The tubulated between future plasma proposed form an arc upon scission of vesicle. Therefore, may gradually converted those both vesicles membrane.

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