The occurrence and distribution of certain polypeptides within the human carotid body.
作者： Paul Smith , John Gosney , Donald Health , Heather Burnett
DOI: 10.1007/BF00313536
关键词:
摘要: Both carotid bodies from 26 patients coming to necropsy were fixed in 10% neutral buffered formalin and sections 4 μm thick stained for various peptides by use of the immunogold technique. The results show that human body contains met- leu-enkephalin, substance P, vasoactive intestinal peptide (VIP), neurotensin bombesin. distribution these six within differs. Thus leu-enkephalin are both present predominantly glomic chief cells but with a marked tendency favour dark variant cells. Substance P VIP weak immunoreactivity comparison enkephalins all three variants cell. Neurotensin shows weakest is restricted few minority cases. Bombesin also strong reaction arteries arterioles. In vessels bombesin appears be confined smooth muscle media we cannot say whether it secreted them or merely bound receptor sites on their membranes. These findings related quantitative data concentration previous paper which associated.
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