Disseminated histoplasmosis in an Atlantic bottlenose dolphin (Tursiops truncatus).

摘要: An approximately 37-yr-old female Atlantic bottlenose dolphin (Tursiops truncatus) died after a 4-mo illness characterized by intermittent anorexia, lethargy, mild neutrophilic leukocytosis, and nonregenerative anemia. At necropsy, the lungs were diffusely consolidated, histopathology of revealed severe pneumonia with macrophages containing clusters numerous yeast cells. Inflammatory lesions also found in pulmonary, mediastinal, prescapular, duodenal lymph nodes, spleen, liver, kidneys, urinary bladder, pancreas, right adrenal gland, pyloric stomach. Histomorphology, fungal culture, polymerase chain reaction analysis indicated that fungus was Histoplasma capsulatum var. capsulatum. This is first report histoplasmosis cetacean.