Synthesis, characterization and antibacterial property of strontium half and totally substituted hydroxyapatite nanoparticles

作者: Yingguang Lin , Zhuoru Yang , Jiang Cheng , Lianshi Wang

DOI: 10.1007/S11595-006-4475-2

关键词:

摘要: Nanoparticles of hydroxyapatite(HAP), strontium half substituted hydroxyapatite (SrCaHAP) and totally (SrHAP) were prepared by sol-gel-supercritical fluid drying (SCFD) method. The nanoparticles characterized element content analysis, FT-IR, XRD TEM, the effects substitution on crystal structure, crystallinity, particle shape antibacterial properties Escherichia coli, Staphylococcus aureus, Lactobacillus researched. Results show that can substitute for calcium enter structure apatite according to initial atomic ratios Sr/[Sr+Ca] as 0.5, 1. decreases IR wavenumbers SrCaHAP SrHAP, changes morphology from short rod shaped HAP needle SrCaHAP, back SrHAP. crystallinity is higher than but lower Moreover, property SrHAP are improved after strontium.

参考文章(12)
T. N KIM, Q. L FENG, J. O KIM, J WU, H WANG, G. C CHEN, F. Z CUI, Antimicrobial effects of metal ions (Ag+, Cu2+, Zn2+) in hydroxyapatite. Journal of Materials Science: Materials in Medicine. ,vol. 9, pp. 129- 134 ,(1998) , 10.1023/A:1008811501734
Shi Wenhua, Analysis on the Difference between Synthetic Hydroxyapatite and Bone Apatite 武汉理工大学学报-材料科学版(英文版). ,(2005)
Wang You-fa, Yan Yu-hua, Li Mei-juan, Jiang Xin, Influential factors on morphology of hydroxyapatite crystals Journal of Wuhan University of Technology-Mater. Sci. Ed.. ,vol. 18, pp. 33- 36 ,(2003) , 10.1007/BF02835084
I. Gedalia, D. Almog, S. Yariv, Effects of strontium and fluoride uptakes on the solubility of powdered enamel. Caries Research. ,vol. 11, pp. 287- 292 ,(1977) , 10.1159/000260280
Hae-Won Kim, Young-Hag Koh, Young-Min Kong, Jun-Gu Kang, Hyoun-Ee Kim, Strontium substituted calcium phosphate biphasic ceramics obtained by a powder precipitation method Journal of Materials Science: Materials in Medicine. ,vol. 15, pp. 1129- 1134 ,(2004) , 10.1023/B:JMSM.0000046395.76435.60
A. Bigi, E. Foresti, M. Gandolfi, M. Gazzano, N. Roveri, Inhibiting effect of zinc on hydroxylapatite crystallization Journal of Inorganic Biochemistry. ,vol. 58, pp. 49- 58 ,(1995) , 10.1016/0162-0134(94)00036-A
J. Christoffersen, M.R. Christoffersen, N. Kolthoff, O. Bärenholdt, Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone mineral detection Bone. ,vol. 20, pp. 47- 54 ,(1997) , 10.1016/S8756-3282(96)00316-X
Dagang Guo, Kewei Xu, Xiaoyun Zhao, Yong Han, Development of a strontium-containing hydroxyapatite bone cement. Biomaterials. ,vol. 26, pp. 4073- 4083 ,(2005) , 10.1016/J.BIOMATERIALS.2004.10.032
Fa-qin Dong, Guo-wu Li, Zhi-gang Sun, Gang Shen, Qi-ming Feng, Qun-wei Dai, Preparation and antimicrobial ability of natural proous antibacterial materials Journal of Central South University of Technology. ,vol. 12, pp. 370- 375 ,(2005) , 10.1007/S11771-005-0163-1
Guoqiang Chen, Qngling Feng, Kai Zhao, Antibacterial effects of silver loaded hydroxyapatite Tsinghua Science & Technology. ,vol. 4, pp. 1570- 1573 ,(2012)