Organoarsenicals in Seafood: Occurrence, Dietary Exposure, Toxicity, and Risk Assessment Considerations - A Review.
作者： Caleb Luvonga , Catherine A. Rimmer , Lee L. Yu , Sang B. Lee
关键词:
摘要: Diet, especially seafood, is the main source of arsenic exposure for humans. The total content a diet offers inadequate information assessment toxicological consequences intake, which has impeded progress in establishment regulatory limits food. Toxicity assessments are mainly based on inorganic arsenic, well-characterized carcinogen, and arsenobetaine, organoarsenical seafood. Scarcity toxicity data organoarsenicals, predominance arsenobetaine as an organic species led to assumption their nontoxicity. Recent toxicokinetic studies show that some organoarsenicals bioaccessible cytotoxic with demonstrated toxicities like pernicious trivalent underpinning need speciation analysis. investigate compare bioavailability, metabolic transformation, elimination from body well-established physiological apparent. This review provides overview occurrence human associated consumption
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