Verapamil treatment for women with bipolar disorder

摘要: Abstract Background: Additional pharmacological treatments are needed for patients with bipolar disorder. We describe our experience verapamil in an inclusive, sequential series of outpatient women (some pregnant) Methods: All who were prescribed disorder ( n = 37) included. used the criterion 50% reduction scores on Mania Rating Scale or Hamilton Depression to define response treated acute episode hypomania/mania depression, respectively. For euthymic chose maintenance treatment, we evaluated whether they met criteria a recurrent during therapy. Results: Treatment episodes was initiated 28 women. Of depression and mania, 39% 100% responded, Seven nine (77%) mixed states responded: all seven improved mania scale, two responded scales as well. Six eight received continuation therapy remained Conclusions: These data provide evidence that is effective mania. The rate compares favorably other mood stabilizers. After decades case reports underpowered clinical trials, must definitively study efficacy gender specificity