Developmental physiology of the zebrafish cardiovascular system

作者: John D. Mably , Sarah J. Childs

DOI: 10.1016/S1546-5098(10)02906-7

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摘要: Publisher Summary This chapter discusses the developmental physiology of zebrafish cardiovascular system. The strength as a genetic model system enables systematic dissection interactions among genes in an intact vertebrate organism and bolsters its potential for screens or chemical modifiers physiology. Phenotype-driven that disrupt normal growth function offer opportunity to understand biology heart vascular pathways may be disrupted disease. Cardiac is essential flow, which turn determines aspects cardiac morphology. cardiomyocytes originate ventral–marginal zone, involute, migrate through lateral plate mesoderm generate tube precursor at midline, cone with pre-ventricular cells pointing apically. posterior forms vessel blood precursors. It adjacent intermediate kidney.

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