Analysis of fluid separation in microfluidic T-channels

作者: Xiangdong Xue , Mayur K. Patel , Maïwenn Kersaudy-Kerhoas , Marc P.Y. Desmulliez , Chris Bailey

DOI: 10.1016/J.APM.2011.07.009

关键词:

摘要: Abstract The behaviour of a fluid, which may contain particle suspensions, flowing in micro-dimensional channels is governed by both viscous and surface tension forces as well high shear rates geometric effects such bifurcations, constriction, surface-to-volume ratio. This paper discusses some the key design factors affecting fluid micro-engineered products containing main channel, constriction side channel bifurcations. Differences at macro micro-scales are discussed. dynamic bulk characterised terms of: (i) properties, (ii) governing physics (iii) microchannel features. At this stage analysis fluids assumed to be Newtonian single phase, where any suspension represented through density viscosity. Based on these assumptions Computational Fluid Dynamics (CFD) used investigate effect product inlet outlet boundary conditions flow behaviour. Discussions provided how can affect separation efficiency. In particular, so called pull-design whereby pulled out device outlet, shown offer better performance compared mode operation pushed into inlet. It also observed that increasing pressure achieve balanced rate ratio leads uniform among all

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