Main Risk Factors Related to Activities of Daily Living in Non-Dialysis Patients with Chronic Kidney Disease Stage 3-5: A Case-Control Study.

摘要: Introduction Elderly people are at increased risk of falls, disability and death due to reduced functional reserve, decline in multiple systems functions, which affects their activities daily living (ADL) eventually develop into frailty. The ADL assessment is conducive early detection avoid further serious situations. Previous studies on patients' with chronic kidney disease (CKD) mainly focused dialysis patients. Little information available on non-dialysis Patients Methods A total 303 elderly patients CKD stage 3-5 who were admitted our hospital selected. evaluation was performed admission, Barthel index (BI) as the tool. They divided two groups based BI (≥60 <60). Demographic information, lifestyle clinical profile collected. factors related analyzed by univariate multivariate models. Results data enrolled this study analyzed. average age 84.48± 7.14 years 62.05% male. There 88 (29.04%) <60 group 215 (70.96%) ≥60 group. subjects 87.47 ± 5.85 83.26± 7.28 years, respectively. On analysis, impairment associated many factors, such age, body mass index, blood lipid, heart rate, smoking history, Charlson comorbidity (CCI), hemoglobin, serum albumin, BNP, eGFR, etc. Multivariate logistic regression showed that (OR 1.08, 95% CI 1.00-1.17, P=0.0390), 4.75, 1.17-19.30, P=0.0295), albumin 0.80, 0.70-0.92, P=0.0012) independent impairment. Conclusion Decline independently correlated albumin. its influential deserve attention.