Role of admission serum albumin levels in patients with intracerebral hemorrhage

作者: Kaustubh Limaye , Ju Dong Yang , Archana Hinduja

DOI: 10.1007/S13760-015-0504-2

关键词:

摘要: Low serum albumin levels have been reported to be an independent predictor of increased morbidity and mortality in multiple disease conditions. The aim our study was identify the impact low on outcomes at discharge patients with intracerebral hemorrhage. We retrospectively reviewed prospective database hemorrhage from January 2010 December 2011. Patients were dichotomized into two groups based their upon admission. Hypoalbuminemia defined as ≤3.4 g/dl. compared using Fisher’s exact test for categorical variables t continuous variables. Poor outcome death or a long-term nursing facility (modified Rankin Score 4–6). Out 97 admitted hemorrhage, 90 met inclusion criteria (42 had normal 48 hypoalbuminemia). baseline characteristics, risk factors, etiology, location volume admission blood glucose, white cell count, length hospital stay, intensive care unit complications similar between both groups. Although hypoalbuminemia did not in-hospital (28 vs 24 %, p = 0.635), there significant increase poor (59 31 0.009) (OR 1.8; 95 % CI; 1.2–2.8). Similar other diseases, associated functional This will need confirmed larger studies before adopting therapeutic preventive strategies future.

参考文章(25)
Kazunori Toyoda, Cerebrorenal Interaction and Stroke Contributions To Nephrology. ,vol. 179, pp. 1- 6 ,(2013) , 10.1159/000346944
J P Broderick, T G Brott, J E Duldner, T Tomsick, G Huster, Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality. Stroke. ,vol. 24, pp. 987- 993 ,(1993) , 10.1161/01.STR.24.7.987
Deepa M. Gopal, Andreas P. Kalogeropoulos, Vasiliki V. Georgiopoulou, Wilson W.H. Tang, Amanda Methvin, Andrew L. Smith, Douglas C. Bauer, Anne B. Newman, Lauren Kim, Tamara B. Harris, Stephen B. Kritchevsky, Javed Butler, Serum albumin concentration and heart failure risk American Heart Journal. ,vol. 160, pp. 279- 285 ,(2010) , 10.1016/J.AHJ.2010.05.022
Ola G. Nilsson, Arne Lindgren, Lennart Brandt, Hans Säveland, Prediction of death in patients with primary intracerebral hemorrhage: a prospective study of a defined population Journal of Neurosurgery. ,vol. 97, pp. 531- 536 ,(2002) , 10.3171/JNS.2002.97.3.0531
Thomas A. Ryan, Mohamed Y. Rady, C. Allen Bashour, Marvin Leventhal, Bruce Lytle, Norman J. Starr, Predictors of outcome in cardiac surgical patients with prolonged intensive care stay Chest. ,vol. 112, pp. 1035- 1042 ,(1997) , 10.1378/CHEST.112.4.1035
Marco Stein, Markus Luecke, Matthias Preuss, Dieter-Karsten Boeker, Andreas Joedicke, Matthias F Oertel, Spontaneous intracerebral hemorrhage with ventricular extension and the grading of obstructive hydrocephalus: the prediction of outcome of a special life-threatening entity. Neurosurgery. ,vol. 67, pp. 1243- 1252 ,(2010) , 10.1227/NEU.0B013E3181EF25DE
Kaj Anker Jørgensen, Erik Stoffersen, On the inhibitory effect of albumin on platelet aggregation Thrombosis Research. ,vol. 17, pp. 13- 18 ,(1980) , 10.1016/0049-3848(80)90289-3
B. N. Becker, Y. T. Becker, D. M. Heisey, G. E. Leverson, B. H. Collins, J. S. Odorico, A. M. D'Alessandro, S. J. Knechtle, J. D. Pirsch, H. W. Sollinger, The impact of hypoalbuminemia in kidney-pancreas transplant recipients. Transplantation. ,vol. 68, pp. 72- 75 ,(1999) , 10.1097/00007890-199907150-00014
Ruijun Ji, Haipeng Shen, Yuesong Pan, Penglian Wang, Gaifen Liu, Yilong Wang, Hao Li, Xingquan Zhao, Yongjun Wang, None, A novel risk score to predict 1-year functional outcome after intracerebral hemorrhage and comparison with existing scores Critical Care. ,vol. 17, pp. 1- 10 ,(2013) , 10.1186/CC13130
Jean-Louis Vincent, Marc-Jacques Dubois, Roberta J. Navickis, Mahlon M. Wilkes, Hypoalbuminemia in Acute Illness: Is There a Rationale for Intervention? A Meta-Analysis of Cohort Studies and Controlled Trials Annals of Surgery. ,vol. 237, pp. 319- 334 ,(2003) , 10.1097/01.SLA.0000055547.93484.87