Factors associated with late presentation for HIV/AIDS care in Harare City, Zimbabwe, 2015

作者: Howard Nyika , Owen Mugurungi , Gerald Shambira , Notion Tafara Gombe , Donewell Bangure

DOI: 10.1186/S12889-016-3044-7

关键词:

摘要: Despite widespread awareness and publicity concerning Human Immunodeficiency Virus (HIV) care advances in treatment, many patients still present late their HIV disease. Preliminary review of the Antiretroviral Therapy (ART) registers at Wilkins Beatrice Road Hospitals, both located Harare, indicated that 67 71 % enrolled into HIV/AIDS presented with baseline CD4 18 years) a who had >200/uL or WHO clinical stage 1 2 first presentation 2014. Written informed consent was obtained from all study participants. A total 268 participants were recruited (134 cases 134 controls). Independent risk factors for illness being reason test (Adjusted Odds Ratio [aOR] =7.68, 95 % CI = 4.08, 14.75); Being male (aOR = 2.84, CI = 1.50, 5.40) and; experienced stigma (aOR = 2.99, CI = 1.54, 5.79). protective receiving information on (aOR = 0.37, CI = 0.18, 0.78) earning more than US$250 per month (aOR = 0.32, CI = 0.76, 0.67). Median duration between reported positive result enrolment pre-ART 2 days (Q1 = 1 day; Q3 = 30 days) among 30 days (Q1 = 3 days; Q3 = 75 days) controls. Late Harare City relate to patient’s sex, getting test, related information, experiencing monthly income. Based this evidence we recommended targeted interventions optimize early access testing care.

参考文章(18)
Christopher S. Krawczyk, Ellen Funkhouser, J Michael Kilby, Richard A. Kaslow, Amita K. Bey, Sten H. Vermund, Factors Associated with Delayed Initiation of HIV Medical Care Among Infected Persons Attending a Southern HIV/AIDS Clinic Southern Medical Journal. ,vol. 99, pp. 472- 481 ,(2006) , 10.1097/01.SMJ.0000215639.59563.83
C. Louis, L. C. Ivers, M. C. Smith Fawzi, K. A. Freedberg, A. Castro, Late presentation for HIV care in central Haiti: factors limiting access to care. Aids Care-psychological and Socio-medical Aspects of Aids\/hiv. ,vol. 19, pp. 487- 491 ,(2007) , 10.1080/09540120701203246
Jesús Castilla, Paz Sobrino, Luis de la Fuente, Isabel Noguer, Luis Guerra, Francisco Parras, Late diagnosis of HIV infection in the era of highly active antiretroviral therapy: consequences for AIDS incidence. AIDS. ,vol. 16, pp. 1945- 1951 ,(2002) , 10.1097/00002030-200209270-00012
Timothy R. Sterling, Richard E. Chaisson, Richard D. Moore, HIV-1 RNA, CD4 T-lymphocytes, and clinical response to highly active antiretroviral therapy. AIDS. ,vol. 15, pp. 2251- 2257 ,(2001) , 10.1097/00002030-200111230-00006
Stephen D Lawn, Landon Myer, Catherine Orrell, Linda-Gail Bekker, Robin Wood, Early mortality among adults accessing a community-based antiretroviral service in South Africa: implications for programme design. AIDS. ,vol. 19, pp. 2141- 2148 ,(2005) , 10.1097/01.AIDS.0000194802.89540.E1
Maeva A Bonjour, Morelba Montagne, Martha Zambrano, Gloria Molina, Catherine Lippuner, Francis G Wadskier, Milvida Castrillo, Renzo N Incani, Adriana Tami, None, Determinants of late disease-stage presentation at diagnosis of HIV infection in Venezuela: a case-case comparison. Aids Research and Therapy. ,vol. 5, pp. 6- 6 ,(2008) , 10.1186/1742-6405-5-6
JBM Ddamulira, E Rutebemberwa, E Tumushabe, F Nuwaha, Factors associated with delayed diagnosis of HIV infection in Mukono district, Uganda East African Medical Journal. ,vol. 86, pp. 411- 416 ,(2010) , 10.4314/EAMJ.V86I9.54162
Jeffrey H. Samet, Kenneth A. Freedberg, Jacqueline B. Savetsky, Lisa M. Sullivan, Michael D. Stein, Understanding delay to medical care for HIV infection: the long-term non-presenter. AIDS. ,vol. 15, pp. 77- 85 ,(2001) , 10.1097/00002030-200101050-00012
Katharina Kranzer, Jennifer Zeinecker, Philip Ginsberg, Catherine Orrell, Nosindiso N. Kalawe, Stephen D. Lawn, Linda-Gail Bekker, Robin Wood, Linkage to HIV Care and Antiretroviral Therapy in Cape Town, South Africa PLoS ONE. ,vol. 5, pp. e13801- ,(2010) , 10.1371/JOURNAL.PONE.0013801