METHOD FOR PREDICTION OF EARLY RECURRENCE IN PATIENTS WITH CLASSICAL HODGKIN'S LYMPHOMA

摘要: FIELD: medicine.SUBSTANCE: invention refers to medicine, oncohematology, namely a prediction of developing early recurrence in patients with classical Hodgkin's lymphoma after high-dose chemotherapy and transplantation autologous hemopoietic stem cells (auto-THSC). That is ensured by flow cytometry an estimate the relative content one lymphocyte populations using threshold value, according invention, when lymphopenia emerges patient's peripheral blood, absolute amount CD45CD3T-cells, CD45CD3T-cells more than 717 cells/mcl, higher probability auto-THSC, if less preserving remission within first year auto-THSC.EFFECT: provides possibility isolate LH, having significantly HDCT autologous-THSC, which enables timely correct further management patient, also simple economic, due absence special sample preparation necessity spend intracellular estimation maintenance marker, use minimum quantity investigated material additional blood intake period exit patient from leukopenia.1 cl, 2 dwg, 4 ex