Predicting prognosis in classic hodgkin lymphoma

作者: Christian Steidl , David Scott , Randy Gascoyne

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摘要: Predictor genes and methods for determining prognosis in classic Hodgkin's lymphoma (cHL) are described herein. Expression levels of predictor ALDH1A1, APOL6, B2M, CD300A, CD68, CXCL11, GLUL, HLA-A, HLA-C, IFNG, IL15RA, IRF1, LMO2, LYZ, PRF1, RAPGEF2, RNF144B, STAT1, TNFSF10, WDR83, CCL17, COL6A1, PDGFRA used to derive a score within prognostic model. Measurement expression may involve counting RNA molecules using digital profiling, such as the NanoStringTM platform. The is compared threshold indicative outcome. Associated kits, commercial packages, panels biomarkers, uses also provided.

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