Detection of serum fibrinogen and fibrin degradation products

摘要: Abstract Six assay systems for serum fibrin degradation products (tanned red cell hemagglutination inhibition immunoassay (TRCHII), staphylococcal clumping test, Fi flocculation, immunodiffusion and anticoagulant assay) were compared reactivity with plasmin digests of fibrinogen fibrin, purified obtained from patients suspected having circulating products. The TRCHII reacts best undigested the intermediate fragments X Y. Although less reactive fragments, test is as reliable serums, both react about 90 per cent serums. This suggests that complexes monomer or fragment may be responsible positive results One patient defibrination syndrome one therapeutic thrombolysis studied in detail respect to usefulness six reflecting presence a hemorrhagic diathesis. flocculation probably greatest value emergency clinical situations, it rapid simple, yet consistently sensitive levels cause abnormal bleeding.