Clinical manifestations and risk factors of anastomotic leakage after low anterior resection for rectal cancer.

摘要: Background Anastomotic leakage is a common complication that can be associated with catastrophic consequences. However, the risk factors and incidence of anastomotic vary considerably among clinical studies because lack standardized definition, course appropriate treatment options. The aim this study was to identify classify manifestations analyse possible after low anterior resection. Methods From January 2009 June 2010, 632 patients underwent resection for primary colorectal cancer at Samsung Medical Center. Patients only one anastomosis were included from prospectively collected medical database. Results The overall rate 6.0% (n = 38). In cases generalized leakage, selected surgical management, regardless having protective enterostomy time occurrence, had better outcomes. Protective did not have preventive effect lower leakage. confined inflammation pelvic cavity (P 0.045) no intervention initially needed. Male gender 0.021, relative (RR) 2.680, 95% confidence interval (CI) 1.164–6.171) side-to-end/J pouch-to-end 0.012, RR 2.696, CI 1.249–5.818) significant affected leakage. Conclusion Surgical management best choice A diminished occurrence consequent management; therefore, fragile high are recommended undergo enterostomy.