Preparation of poly(ε-caprolactone)-based tissue engineering scaffolds by stereolithography.
作者： Laura Elomaa , Sandra Teixeira , Risto Hakala , Harri Korhonen , Dirk W. Grijpma
DOI: 10.1016/J.ACTBIO.2011.06.039
关键词:
摘要: A photocrosslinkable poly(e-caprolactone) (PCL)-based resin was developed and applied using stereolithography. No additional solvents were required during the structure preparation process. Three-armed PCL oligomers of varying molecular weights synthesized, functionalized with methacrylic anhydride, photocrosslinked, resulting in high gel content networks. Stereolithography used to build designed porous scaffolds containing macromer, Irgacure 369 photoinitiator, inhibitor dye. suitable viscosity obtained by heating curing The precisely matched computer-aided designs, no observable material shrinkage. average porosity 70.5 ± 0.8%, pore size 465 μm. network highly interconnected. photocrosslinkable, biodegradable is well suited for solvent-free fabrication tissue engineering
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