Prevalence of molecular markers of sulfadoxine-pyrimethamine and artemisinin resistance in Plasmodium falciparum from Pakistan.

作者: Adnan Yaqoob , Aamer Ali Khattak , Muhammad Faisal Nadeem , Huma Fatima , Gillian Mbambo

DOI: 10.1186/S12936-018-2620-Y

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摘要: Background In Pakistan, artesunate (AS) in combination with sulfadoxine–pyrimethamine (SP) is the recommended treatment for uncomplicated Plasmodium falciparum malaria. Monitoring molecular markers of anti-malarial drug resistance crucial early detection and containment parasite to treatment. Currently, no data are available on artemisinin (K13 mutations) P. isolates from Pakistan. In this study, prevalence mutations associated SP was estimated different regions

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