Solvent damage during free cell catalysis and its avoidance: studies of 11α-hydroxylation of progesterone by Aspergillus ochraceus

作者: E.G. Ceen , J.P.R. Herrmann , P. Dunnill

DOI: 10.1016/0141-0229(87)90061-5

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摘要: Abstract The solvent tolerance of the progesterone 11α-hydroxylase system Aspergillus ochraceus has been defined and, given its limited extent for conventional organic solvents, a number natural oils have examined. They found superior and represent an interesting class reactants partial polarity. study emphasizes that solvents products biocatalytic action on must often be partially polar not interact strongly with cellular lipids.

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