Antibacterial and antibiotic-potentiation activities of some Cameroonian food plants against multi-drug resistant gram-negative bacteria.

摘要: (7) In the present work, we investigated antibacterial activity of some commonly used food plants in Cameroon against multidrug resistant (MDR) Gram- negative bacteria. These include Zingiber offi cinale Roscoe, Thymus vulgaris L., Cymbopogon citratus Stapf., Petroselinum crispum Ngn., Apium graveolens Ocimum basilicum Linn., Allium porrum Welus., Gnetum africanum Eucalyptus robusta gratissimum L. and Capsicum annuum The study was also extended to evaluation potencies above plant extracts increase antibiotics MDR strains. role bacterial effl ux pumps resistance studied. ABSTRACT Objective: To evaluate : vitro properties ability potentiate common effects methanol 11 Cameroonian on 29 Gram-negative bacteria expressing phenotypes. Methods: antimicrobial performed using broth microdilution method. phytochemical screening these standard methods. Results: basilicum, possessed an all studied from G. E. were most active with lowest minimal inhibitory concentration 64 μg/mL Escherichia coli AG100A for both Klebsiella pneumoniae K24 africanum. When tested presence phenylalanine-arginine β-Naphtylamide . (PAβN), pump inhibitor, extract Robusta showed best activities good synergistic effects, improving about 85% cases. Conclusion: overall results obtained provide baseline information use treatment infections. KEYWORDS plants, Cameroon, bacteria,