Accidental plant poisoning with Colchicum autumnale: report of two cases.
作者： D Vitezić , D Cuculić , I Visković , N Brncić , A Dirlić
DOI:
关键词:
摘要: Colchicine poisoning is a rare but serious and potentially fatal event, which results from food or overdose with drugs containing colchicine, no currently available antidote. We report two cases of plant Colchicum autumnale, in the patients had identical initial symptoms developed extremely different clinical courses. One patient recovered after only moderate gastroenteritis liver injury, whereas other died rapid progressive multiple organ failure 52 h ingestion. recommend that all suspected colchicine intoxication due to its unpredictable outcome should be managed according principles intensive care, irrespective actual degree poisoning.
irb.hr
mefst.hr 参考文章(13)
Iain M. McIntyre, Andrew R. Ruszkiewicz, Kerryn Crump, Olaf H. Drummer, Death Following Colchicine Poisoning Journal of Forensic Sciences. ,vol. 39, pp. 13598J- 286 ,(1994) , 10.1520/JFS13598J
Richard J. Simons, Douglas W. Kingma, Fatal colchicine toxicity The American Journal of Medicine. ,vol. 86, pp. 356- 357 ,(1989) , 10.1016/0002-9343(89)90315-X
G. G. Borisy, E. W. Taylor, THE MECHANISM OF ACTION OF COLCHICINE : Binding of Colchincine-3H to Cellular Protein Journal of Cell Biology. ,vol. 34, pp. 525- 533 ,(1967) , 10.1083/JCB.34.2.525
Roger D Harris, Mark J Gillett, Colchicine poisoning—overview and new directions Emergency Medicine Australasia. ,vol. 10, pp. 161- 167 ,(2009) , 10.1111/J.1442-2026.1998.TB00674.X
J.M. Scherrmann, M. Urtizberea, P. Pierson, N. Terrien, The effect of colchicine-specific active immunization of colchicine toxicity and disposition in the rabbit Toxicology. ,vol. 56, pp. 213- 222 ,(1989) , 10.1016/0300-483X(89)90134-0
Chaim Putterman, Eldad Ben-Chetrit, Yoseph Caraco, Micha Levy, Colchicine intoxication: clinical pharmacology, risk factors, features, and management. Seminars in Arthritis and Rheumatism. ,vol. 21, pp. 143- 155 ,(1991) , 10.1016/0049-0172(91)90003-I
J. Stephan Stapczynski, Robert J. Rothstein, Wallace A. Gaye, James T. Niemann, Colchicine overdose: report of two cases and review of the literature Annals of Emergency Medicine. ,vol. 10, pp. 364- 369 ,(1981) , 10.1016/S0196-0644(81)80239-9
D Heaney, CB Derghazarian, GF Pineo, MA Ali, Massive colchicine overdose: a report on the toxicity. The American Journal of the Medical Sciences. ,vol. 271, pp. 233- 238 ,(1976) , 10.1097/00000441-197603000-00014
Michael Klintschar, Christine Beham-Schmidt, Herbert Radner, Gerald Henning, Peter Roll, Colchicine poisoning by accidental ingestion of meadow saffron (Colchicum autumnale): pathological and medicolegal aspects Forensic Science International. ,vol. 106, pp. 191- 200 ,(1999) , 10.1016/S0379-0738(99)00191-7
S. Mendis, Colchicine cardiotoxicity following ingestion of Gloriosa superba tubers. Postgraduate Medical Journal. ,vol. 65, pp. 752- 755 ,(1989) , 10.1136/PGMJ.65.768.752