Quantitative characterization of articular cartilage using Mueller matrix imaging and multiphoton microscopy

摘要: The collagen meshwork in articular cartilage of chicken knee is characterized using Mueller matrix imaging and multiphoton microscopy. Direction degree dispersion the fibers superficial layer are found a Fourier transform image-analysis technique second-harmonic generated image. images used to acquire structural data from intermediate where too small be resolved by optical microscopy, providing powerful multimodal measurement technique. Furthermore, we show that provides more information about tissue compared standard polarization combination these techniques can find use improved diagnosis diseases cartilage, histopathology, additional for accurate biomechanical modeling cartilage.