Adenoma-like adenocarcinoma: clinicopathologic characterization of a newly recognized subtype of colorectal carcinoma.

作者: Iván A. González , Philip S. Bauer , Jingxia Liu , Deyali Chatterjee

DOI: 10.1016/J.HUMPATH.2020.09.008

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摘要: Summary The 5th edition of the World Health Organization (WHO) Classification Tumours (Digestive System) recognizes a new subtype colorectal adenocarcinoma, called adenoma-like adenocarcinoma. In this study, we sought to determine its clinicopathologic associations and how it is comparable with no special type (NOS). We retrospectively reviewed all available archival slides stage I–III colonic adenocarcinoma resection specimens at our institution from 2013 2016.Ninety-one cases were classified as 251 NOS. Of cases, majority (65 71%) composed exclusively features, designated pure whereas in rest, component morphology was more than 50% but less 100%, mixed Compared NOS, significantly associated absence tumor budding (P

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