Photodynamische Diagnose (PDD) und Therapie (PDT) des oberflächlichen Harnblasenkarzinoms
作者： M. Kriegmair , R. Baumgartner
DOI: 10.1007/978-3-662-08253-9_5
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摘要: Die photodynamische Diagnostik und Therapie beruht auf der Wechselwirkung zwischen Licht, in Regel Laserlicht, fluoreszierenden lichtempfindlichen Substanzen, sog. Photosensibilisatoren molekularem Sauerstoff im Gewebe (Dougherty u. Marcus 1992). Seit etwa 1960 ist bekannt, das Porphyringemi-sche, wie Hamatoporphyrinderivat (HpD) nach i. v.-Verabreichung Tumoren erhohter Konzentration vorliegen, verglichen zur gesunden Umgebung (Lipson Baldes 1960). Im Jahr 1975 wurde die erste Photodynamische beim Harnblasenkarzinom durchgefuhrt (Kelly Shell 1976).
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