The Photodynamic Properties of a Particular Hematoporphyrin Derivative

摘要: In 1898 Oscar Raab, while a student in Tappeiner's laboratory, recognized that paramecia were sensitized to light by the aniline dye, acridine. This finding led extensive studies Tappeiner and Jodlbauer their associates,9,19,-21and introduction of term "photodynamic action," used 1904. The use hematoporphyrin study photodynamics came soon after original Raab. first was Hausmann 1908. He reported destruction red blood cells described detail symptoms mice on exposure light.6-8Pfeiffer found same thing guinea pigs, 1913 Meyer-Betz himself similar which lasted two months. During subsequent years, many studies1-4were carried out using hydrochloride prepared according classic method Nencki Zaleski. However, Schwartz associates16,17have