Reduced body weight and adiposity with a high-protein diet improves functional status, lipid profiles, glycemic control, and quality of life in patients with heart failure: a feasibility study.

摘要: Background The effectiveness of high-protein (HP) diets in reducing body weight and adiposity potentially improving clinical outcomes heart failure (HF) is not known. Objective This feasibility study was conducted to evaluate the impact 3 dietary interventions on adiposity, functional status, lipid profiles, glycemic control, quality life (QOL) overweight obese patients with HF type 2 diabetes mellitus. Design Fourteen a mass index greater than 27 kg/m2 were randomized an HP diet, standard protein or conventional diet. Data obtained at baseline 12 weeks. Results There no significant differences age (59 +/- 10 years), sex (78% male), New York Heart Association class (43% II, 57% III), etiology left ventricular ejection fraction (26 7) between groups baseline. Patients diet demonstrated significantly reductions (P = .005), percent fat .036), total cholesterol .016), triglyceride concentrations .034), low-density lipoprotein .041) improvements status (6-minute walk [P .010] VO2 peak .003]), high-density .006), physical QOL scores .022) compared those diets. Conclusion A 12-week resulted moderate loss reduced small sample that associated QOL. However, these preliminary findings must be confirmed studies more participants long-term follow-up.