PTY 2 As DPP-IV Inhibitor Prevents Intestinal Cell’s Apoptosis
作者： Shivani Srivastava , Harsh Pandey , Surya K Singh , Yamini Bhusan Tripathi
DOI: 10.1101/670430
关键词:
摘要: ABSTRACT Enhanced DPP-IV expression is found to get enhanced in various intestinal diseases. PTY-2 has already been known have inhibitory potential. This inhibition not yet studied at mRNA level. Increased incretin secretion due could lead suppression of stress & cells apoptosis. Through histological analysis, we morphological damage intestine after STZ injection (65 mg/kg bw) male Charles foster rats. expressions were analyzed by PCR and apoptosis was checked through tunnel assay Bcl 2 expression. The number length villi reduced induced diabetic control, but these damages getting reversed the treatment for 10 days. SOD while that control group along with significant cell reduces upregulating downregulation These recoveries leads short studies explain protective action against damage. Hence, be taken as an herbal disorders case chronic diabetes.
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