Microwave-assisted heteropolyanion-based ionic liquid promoted sustainable protocol to N-heteroaryl amides via N-directing dual catalyzed oxidative amidation of aldehydes
作者： Renzhong Fu , Yang Yang , Weihua Jin , Hui Gu , Xiaojun Zeng
DOI: 10.1039/C6RA20961K
关键词:
摘要: A sustainable procedure for the synthesis of N-heteroaryl amides directly from oxidative amidation aldehydes catalyzed by heteropolyanion-based ionic liquids under microwave-promoted conditions has been reported. The transformation proven to tolerate a wide range and amino heterocycles with different functional groups. Moderate excellent yields, solvent-free media, operational simplicity reusability catalysts are main highlights. Furthermore, proposed N-directing dual-catalysis mechanistic pathway was briefly investigated in this report.
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