Modified IL-12 T cell therapy for the treatment of cancer
作者： Li Shulin , Hu Jiemiao , Xia Xueqing , Zhao Qing-Nan
DOI:
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摘要: Provided herein are chimeric antigen receptor (CAR)-like constructs comprising tumor- targeted and membrane-anchored IL-12. Also provided T cells expressing the CAR- like IL-12 construct. Further, methods of treating cancer administering CAR-like herein.
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