作者: Abraham J. Domb
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摘要: A formulation for the administration of a cyclosporin. This features hydrophilic solvent which is characterized by being lower alkyl ester hydroxyalkanoic acid; and surfactant, preferably combination surfactant with high HLB (hydrophilic/lipophilic balance) at least about 8 low less than 5. Other ingredients are optional, such as fatty acid tricaprin, phospholipid, an ethoxylated fat Cremophor or another similar substance. Optionally, substituted surfactant. The preferred particle size resultant 100 nm, more 60 most from 5 nm to 50 nm. present invention having bioavailability.