作者: Therese Sørlie
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摘要: Recent advances in gene expression profiling and other "omics" technologies have revolutionized cancer research hold the potential of also revolutionizing clinical practice. These high-throughout approaches radically changed our ability to study cells tissues a more comprehensive way. Combined with advanced bioinformatics possibility simulate biological processes computers, this field "systems biology" allows us organism as whole entity. This chapter describes molecular classification characterization breast tumors into distinct subtypes by using DNA microarrays discusses statistical relationships subgroups features disease.