Stratum corneum hydration and skin surface pH in patients with atopic dermatitis.

摘要: Atopic dermatitis (AD) is a chronically relapsing skin disease with genetic predisposition, which occurs most frequently in preschool children. It considered that dryness and pruritus, are always present AD, correlation degradation of the barrier function. Measurement hydration pH value stratum corneum one noninvasive methods for evaluation The aim study was to assess function by measuring surface lesions, perilesional uninvolved AD patients, healthy control group. Forty-two patients were included study: 21 young adult age-matched controls. Capacitance, correlated measured on forearm above areas SM810/CM820/pH900 combined units (Courage AND Khazaka, Germany). mean water capacitance 44.1 ± 11.6 AU (arbitrary units) 60.2 12.4 67.2 8.8 skin. In controls, 74.1 9.2 AU. 6.13 0.52 5.80 0.41 skin, 5.54 0.49 group, 5.24 0.40. values both parameters lesional significantly different (capacitance decreased increased) from recorded same held relation between According results, had worse as compared results this suggested be degraded specifically expressed