Comparison of transepidermal water loss, capacitance and pH values in the skin between intrinsic and extrinsic atopic dermatitis patients.

摘要: Atopic dermatitis (AD), with the prevalence rate of around 10 to 15%, is characterized by an intensely pruritic skin lesions typical distribution and morphology. Recently, AD divided into extrinsic type (ADe) intrinsic (ADi) according laboratory findings associated diseases. ADe well-known for high IgE level, positive response food- or aero-allergens, whereas ADi has clinically similar patterns normal serum levels, negative in vitro test environmental food allergens without atopic To instrumentally evaluate differences involvement functions between ADe, we checked transepidermal water loss (TEWL), capacitance pH both types childhood age-matched control. The proportion was 20% all patients (10/51). Our experiment suggested possible ADe. Antecubital fossa a famous site AD, where showed higher TEWL decreased capacitance. increased sites lower hydration 4 sites, no significant forehead, cheek, back leg.