Antithrombin III Contributes to the Protective Effects of Fresh Frozen Plasma Following Hemorrhagic Shock by Preventing Syndecan-1 Shedding and Endothelial Barrier Disruption.
作者： Ernesto Lopez , Zhanglong Peng , Rosemary A. Kozar , Yanna Cao , Tien C. Ko
DOI: 10.1097/SHK.0000000000001432
关键词:
摘要: ABSTRACTBackground:Endothelial dysfunction during hemorrhagic shock (HS), is associated with loss of cell-associated syndecan-1 (Sdc1) and hyperpermeability. Fresh frozen plasma (FFP) preserves Sdc1 reduces permeability following HS, although the key mediators remain unknown. Antithrombin III (A
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