Meningioma consistency prediction utilizing tumor to cerebellar peduncle intensity on T2-weighted magnetic resonance imaging sequences: TCTI ratio.

摘要: OBJECTIVE Meningioma consistency, firmness or softness as it relates to resectability, affects the difficulty of surgery and, some degree, extent resection. Preoperative knowledge tumor consistency would affect preoperative planning and instrumentation. Several methods prediction have been proposed, but majority lack objectivity reproducibility generalizability other surgeons. In a previous pilot study 20 patients authors proposed new method based on tumor/cerebellar peduncle T2-weighted imaging intensity (TCTI) ratios in comparison with objective intraoperative findings. present they sought validation this method. METHODS Magnetic resonance images from 100 consecutive undergoing craniotomy for meningioma resection were evaluated preoperatively. During grade was prospectively applied lesions by operating surgeon, determined suction and/or cavitron ultrasonic surgical aspirator (CUSA) intensity. Consistency grades A, soft; B, intermediate; C, fibrous. Using MRI sequences, TCTI calculated. Analysis completed ANOVA receiver characteristic curves. RESULTS Of tumors evaluated, 50 classified soft, 29 intermediate, 21 firm. The median ratio firm 0.88; intermediate tumors, 1.5; soft 1.84. One-way comparing these groups statistically significant (p < 0.0001). A single cutoff value 1.41 versus found be 81.9% sensitive 84.8% specific. CONCLUSIONS propose T2-based correlation consistency. This is quantifiable reproducible, which expands its usability. Additionally, places graded continuum clinically meaningful way that could planning.