Autism and epilepsy: Exploring the relationship using experimental models

摘要: The common co-occurrence of autism and epilepsy suggests that certain neurobiological mechanisms are shared between these disorders. In particular, the profusion novel genetic mutations being discovered in points to abnormalities synapse formation function alter balance neuronal excitation inhibition. Animal models can be informative sorting out medical behavioral complexities relationship them. As mechanistic information accrues, it is anticipated mutation- pathway-specific targeted treatments developed.