Electrocatalytic oxidation and selective voltammetric detection of methyldopa in the presence of hydrochlorothiazide in real samples

作者: Somayeh Tajik , Mohammad Reza Aflatoonian , Hadi Beitollahi , Iran Sheikh Shoaie , Zahra Dourandish

DOI: 10.1016/J.MICROC.2020.105182

关键词:

摘要: Abstract The combination of methyldopa and hydrocholorothiazide are used to treat high blood pressure. present research dealt with the synthesis utilization hexagonal-shaped ZnO nanoparticles (NPs) develop a new, sensitive, exclusive electrochemical sensor for detection methyldopa. Thus, we did our examination on via cyclic voltammetry (CV) method, differential pulse (DPV) technique, chronoamperometry (CH) at molybdenum (VI) complex-ionic liquid–ZnO NP modified carbon paste electrode (MCILZNMCPE) in 0.1 M PBS (pH 7.0) solution. use DPV showed linear dependence peak current pH 7.0 solution their concentration ranging between 0.05 300.0 µM. Then, limit (LOD) has been determined be 20.0 nM Ultimately, utilized detecting presence hydrochlorothiazide by DPV.

参考文章(51)
Celso H Oliveira, Rafael E Barrientos-Astigarraga, Mauro Sucupira, Gustavo S Graudenz, Marcelo N Muscará, Gilberto De Nucci, None, Quantification of methyldopa in human plasma by high-performance liquid chromatography-electrospray tandem mass spectrometry application to a bioequivalence study. Journal of Chromatography B. ,vol. 768, pp. 341- 348 ,(2002) , 10.1016/S1570-0232(01)00612-2
Wesley B.S. Machini, Diego N. David-Parra, Marcos F.S. Teixeira, Electrochemical investigation of the voltammetric determination of hydrochlorothiazide using a nickel hydroxide modified nickel electrode Materials Science and Engineering: C. ,vol. 57, pp. 344- 348 ,(2015) , 10.1016/J.MSEC.2015.07.035
Aysegul Kutluay, Mehmet Aslanoglu, Quantification of methyldopa in pharmaceuticals using a glassy carbon electrode modified with carbon nanotubes Chinese Chemical Letters. ,vol. 27, pp. 91- 95 ,(2016) , 10.1016/J.CCLET.2015.04.038
Nagappa L Teradal, Prashanth S Narayan, Jaldappagari Seetharamappa, Ashis K Satpati, None, Electrosensing of an alpha-adrenergic agonist psychoactive methyldopa using a sodium bentonite–graphene oxide nanocomposite Analytical Methods. ,vol. 7, pp. 5611- 5618 ,(2015) , 10.1039/C5AY01021G
Sandeep Kumar, Wandit Ahlawat, Rajesh Kumar, Neeraj Dilbaghi, Graphene, carbon nanotubes, zinc oxide and gold as elite nanomaterials for fabrication of biosensors for healthcare Biosensors and Bioelectronics. ,vol. 70, pp. 498- 503 ,(2015) , 10.1016/J.BIOS.2015.03.062
Jahan Bakhsh Raoof, Nader Teymoori, Mohammad A. Khalilzadeh, Reza Ojani, A high sensitive electrochemical nanosensor for simultaneous determination of glutathione, NADH and folic acid. Materials Science and Engineering: C. ,vol. 47, pp. 77- 84 ,(2015) , 10.1016/J.MSEC.2014.11.012
M.A. El Mhammedi, M. Bakasse, R. Bachirat, A. Chtaini, Square wave voltammetry for analytical determination of paraquat at carbon paste electrode modified with fluoroapatite Food Chemistry. ,vol. 110, pp. 1001- 1006 ,(2008) , 10.1016/J.FOODCHEM.2008.03.005
Sidney Xavier dos Santos, Éder Tadeu Gomes Cavalheiro, Evaluation of the Potentialities of a Carbon Nanotubes/Silicone Rubber Composite Electrode in the Determination of Hydrochlorothiazide Analytical Letters. ,vol. 45, pp. 1454- 1466 ,(2012) , 10.1080/00032719.2012.675499