Osteoradionecrosis of the mandible

作者: Verna Vanderpuye , Alfred Goldson

DOI:

关键词:

摘要: Osteoradionecrosis is a major complication of surgery or trauma in previously irradiated bone the absence tumor persistence. Radiation-induced vascular insufficiency rather than infection causes death. It occurs most commonly mandible after head and neck irradiation. Risk factors include total radiation dose, modality treatment, fraction size dose rate, oral hygiene, timing tooth extractions as well continued use tobacco alcohol. This condition often painful, debilitating, may result significant loss. The recommended treatment guidelines are irrigation, antibiotics, hyperbaric oxygen therapy, surgical techniques, including hemimandibulectomy graft placements.

参考文章(1)
Westermark A, Jensen J, Sindet-Pedersen S, Osteoradionecrosis, pathogenesis, treatment and prevention. Tandlaegebladet. ,vol. 94, pp. 669- ,(1990)