Effects of anesthetic induction with midazolam-propofol and midazolam-etomidate on selected ocular and cardiorespiratory variables in clinically normal dogs.

摘要: Objective—To compare effects of anesthetic induction with midazolam-propofol or midazolam-etomidate on intraocular pressure (IOP), pupillary diameter (PD), pulse rate, blood pressure, and respiratory rate in clinically normal dogs. Animals—18 Procedures—Dogs undergoing ophthalmic surgery received midazolam (0.2 mg/kg, IV) either propofol etomidate (IV) until intubatable. For all dogs, results physical examinations, examinations the nonoperated eye, preanesthetic analyses were normal. Intraocular PD, measured eye at 5 time points: just prior to sequence, after minutes oxygenation via face mask, IV administration midazolam, induction, endotracheal intubation. Results—PD decreased significantly from baseline by 4.4 ± 0.4 mm (mean SD) 5.3 intubation eto...