Exaggerated placental site, consisting of implantation site intermediate trophoblasts, causes massive postpartum uterine hemorrhage: case report and literature review.

摘要: Every year, 14 million cases of obstetric hemorrhage occur worldwide, causing 127,000 maternal deaths. About 75% postpartum are due to atonic uterus, which is loss uterine muscular tone or strength for contraction the uterus after delivery. The prediction therefore important prevention death. However, occurrence difficult before delivery, because precise pathophysiological mechanism trigger this condition remains unclear. Here, we present a case severe uterus. A 35-year-old woman gave birth by vaginal delivery healthy boy. intractable massive removal retained placenta, performed supravaginal hysterectomy as best option survival. Pathological examination showed that implantation site intermediate trophoblasts (ISITs) formed unusually large clumps in decidua, diagnosed exaggerated placental (EPS). EPS thought be consisting an excessive number ISITs. ISITs differentiated from trophoblast lineage process placenta formation. anchor tissue and considered maintain pregnancy, but role these cells Excessive infiltration ISITs, namely EPS, may cause In article, also reviewed literatures on EPS. other reported indicate causes mass formation continuous bleeding, hemorrhage, resulting hysterectomy.